| Name | Edition | Colour | Type | Cost | Power | Rarity | $ |
|---|---|---|---|---|---|---|---|
| Defender en-Vec | NE | White | Creature - Cleric | 3W | 2/4 | Common | 2.69 |
| Defender of Chaos | UL | Red | Summon Knight | 2R | 2/1 | Common | 2.67 |
| Defender of Law | UL | White | Summon Knight | 2W | 2/1 | Common | 2.61 |
| Defender of the Order | LE | White | Creature - Cleric | 3W | 2/4 | Rare | 2.25 |
| Defense Grid | UL | Artifact | Artifact | 2 | Rare | 4.07 | |
| Defense Grid | 8E | Artifact | Artifact | 2 | Rare | 3.39 | |
| Defense Grid | 9E | Artifact | Artifact | 2 | Rare | 3.60 | |
| Defense of the Heart | UL | Green | Enchantment | 3G | Rare | 5.44 | |
| Defensive Formation | US | White | Enchantment | W | Uncommon | 2.80 | |
| Defensive Maneuvers | ON | White | Instant | 3W | Common | 2.23 | |
| Defiant Elf | LE | Green | Creature - Elf | G | 1/1 | Common | 2.23 |
| Defiant Falcon | NE | White | Creature - Rebel | 1W | 1/1 | Common | 2.58 |
| Defiant Stand | PO | White | Sorcery | 1W | Uncommon | 3.56 | |
| Defiant Vanguard | NE | White | Creature - Rebel | 2W | 2/2 | Uncommon | 2.58 |
| Defiant Vanguard | TSS | White | Creature - Human Rebel | 2W | 2/2 | Uncommon | 3.67 |
| Defiling Tears | IN | Black | Instant | 2B | Uncommon | 2.64 | |
| Deflection | IA | Blue | Instant | 3U | Rare | 1.07 | |
| Deflection | 7E | Blue | Instant | 3U | Rare | 0.90 | |
| Deflection | 6E | Blue | Instant | 3U | Rare | 3.52 | |
| Deflection | 5E | Blue | Instant | 3U | Rare | 3.54 | |
| Deflection | 8E | Blue | Instant | 3U | Rare | 0.67 | |
| Deft Duelist | SA | Multi | Creature - Human Rogue | WU | 2/1 | Common | 0.17 |
| Deftblade Elite | LE | White | Creature - Soldier | W | 1/1 | Common | 2.16 |
| Defy Gravity | JU | Blue | Instant | U | Common | 2.07 |